USS Guadalcanal (CVE-60) was a Casablanca class escort carrier of the United States Navy. She was the first ship to carry her name.
She was converted from a Maritime Commission hull by Kaiser Co., Inc., of Vancouver, Washington. Originally Astrolabe Bay (AVG-60), she was reclassified ACV-60 on 20 August 1942 and launched as Guadalcanal (ACV-60) on 5 June 1943, sponsored by Mrs. Alvin I. Malstrom. She was reclassified CVE-60 on 15 July 1943; and commissioned at Astoria, Oregon on 25 September 1943, Captain Daniel V. Gallery in command.
After shakedown training, Guadalcanal performed pilot qualifications out of San Diego, California, and then departed on 15 November 1943, via the Panama Canal, for Norfolk, Va., arriving on 3 December. There she became flagship of Task Group 22.3 (TG 22.3), and with her escort destroyers set out from Norfolk on 5 January 1944 in search of enemy submarines in the North Atlantic. On 16 January, aircraft from Guadalcanal sighted three submarines fueling on the surface, and in a rocket and bombing attack succeeded in sinking U-544. Replenishing at Casablanca, the task group headed back for Norfolk and repairs, arriving on 16 February.